Patients undergoing clinical monitoring for seizures performed a free-recall memory task that asked them to view a series of words on a screen, then repeat back as many as they could remember.Īt the same time, the researchers examined brain activity occurring on slow and fast time scales, also called low- and high-frequency neural activity. ![]() ![]() Though many studies have examined brain networks using non-invasive tools like functional MRI, observations of large-scale networks using direct human-brain recordings have been difficult to secure because these data can only come from neurosurgical patients.įor several years, the Penn team gathered this information from multiple hospitals across the country, allowing the researchers to observe such electrical networks for the first time. This work elucidates the way different regions of the brain communicate during cognitive processes like memory formation. They published their findings in Nature Communications. ![]() student in the Department of Bioengineering and Daniel Rizzuto, director of cognitive neuromodulation at Penn. The research, part of the Restoring Active Memory project, was conducted by Michael Kahana, Penn professor of psychology and principal investigator of the Defense Advanced Research Projects Agency's RAM program Ethan Solomon, an M.D./Ph.D.
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